Research Associate

Job content

AcademicJob CategoryFaculty Non BargainingJob TitleResearch AssociateDepartmentPouladi Laboratory | Department of Medical Genetics | Faculty of Medicine (Mahmoud Pouladi)Posting End DateMarch 2, 2022

Note: Applications will be accepted until 11:59 PM on the day prior to the Posting End Date above.

The Department of Medical Genetics at The University of British Columbia (UBC) invites applications for a fixed-term full-time Research Associate.

This position is located within a health-care facility. Therefore, this position requires successful verification of full vaccination against Covid-19 provided prior to the start date, as required by the provincial health mandate.

The UBC Department of Medical Genetics pursues basic and clinical research for the diagnosis, prevention, and treatment of genetic disease. Our goal is to be a world leader in the research, clinical practice, and teaching of Genetic Medicine. The Department is an inspiring and productive community of scholars dedicated to generating and disseminating knowledge and technical expertise in the field of genetics and genomics. We are a respected source of information and advice to society. While focusing on key areas of genetic medicine, we view diversity of approach and techniques to be an essential strength of our department.

Reporting to Dr. Mahmoud Pouladi , the successful candidate will hold a PhD in Human Genetics and have at least 6 years’ experience in laboratory research involving stem cells; demonstrated experience working with human pluripotent stem cells and their neural differentiation; experience using CRISPR/Cas9 to generate knock-in/knock-out in human pluripotent stem cell lines; experience using IncuCyte live imaging and multi-electrode array systems; experience with flow cytometry and confocal imaging with lasers; experience with flow cytometry and confocal imaging with lasers; experience in molecular biology techniques such as western blotting, immunofluorescence staining and imaging, PCR/qRT-PCR, and immunoprecipitation; and experience analyzing omics data including differential expression and enrichment analyses.

Responsibilities Include

• Development and leading of cellular phenotyping pipeline for neural and non-neural cells; including differentiation of human pluripotent stem cells into neural progenitor cells, neurons, cerebral organoids, oligodendrocytes, microglia, and non-brain cell types (hepatocytes).
• Quality and quantity assessment of generated cellular profiling data
• Proficiency in using the IncuCyte Live Cell Imaging and multi-electrode array systems
• Expertise with genome editing for establishing isogenic human pluripotent cell models
• Experience with forward genetic screens using arrayed/pooled CRISPR/Cas9 mutagenesis
• Performing regular reviews of the relevant literature
• Planning and designing of projects and day-to-day experiments
• Direct generation of multi-omics data (transcriptomics, proteomics)
  

A full job description can be requested at mahmoud.pouladi@ubc.ca.

Salary will be $60,600 per annum for a one (1) year term, commencing June 1, 2022. Please submit your application online at: https://ubc.wd10.myworkdayjobs.com/ubcfacultyjobs . An application package should include a letter of application outlining the applicant’s research interests and experience, accompanied by a detailed curriculum vitae and the names of three references.

Should you have any queries around this position, please contact Human Resources Manager at margarita.reyes@ubc.ca .

Review of applications will begin on March 15, 2022 and continue until the position is filled. The anticipated start date for this position is June 1, 2022 or upon a date to be mutually agreed.

The University of British Columbia is a global centre for research and teaching, consistently ranked among the top 20 public universities in the world. Since 1915, UBC’s entrepreneurial spirit has embraced innovation and challenged the status quo. UBC encourages its students, staff and faculty to challenge convention, lead discovery and explore new ways of learning. At UBC, bold thinking is given a place to develop into ideas that can change the world.

Our Vision: To Transform Health for Everyone.

Ranked among the world’s top medical schools with the fifth-largest MD enrollment in North America, the UBC Faculty of Medicine is a leader in both the science and the practice of medicine. Across British Columbia, more than 12,000 faculty and staff are training the next generation of doctors and health care professionals, making remarkable discoveries, and helping to create the pathways to better health for our communities at home and around the world.

The Faculty - comprised of approximately 2,200 administrative support, technical/research and management and professional staff, as well approximately 650 full-time academic and over 10,000 clinical faculty members - is composed of 19 academic basic science and/or clinical departments, three schools, and 24 research centres and institutes. Together with its University and Health Authority partners, the Faculty delivers innovative programs and conducts research in the areas of health and life sciences. Faculty, staff and trainees are located at university campuses, clinical academic campuses in hospital settings and other regionally based centres across the province.

Equity and diversity are essential to academic excellence. An open and diverse community fosters the inclusion of voices that have been underrepresented or discouraged. We encourage applications from members of groups that have been marginalized on any grounds enumerated under the B.C. Human Rights Code, including sex, sexual orientation, gender identity or expression, racialization, disability, political belief, religion, marital or family status, age, and/or status as a First Nation, Metis, Inuit, or Indigenous person. All qualified candidates are encouraged to apply; however Canadians and permanent residents of Canada will be given priority.